Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G

BACKGROUND: In type 2 diabetes, free fatty acids (FFA) accumulate in microvascular cells, but the phenotypic consequences of FFA accumulation in the microvasculature are incompletely understood. Here we investigated whether saturated FFA induce apoptosis in human microvascular mesangial cells and an...

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Detalles Bibliográficos
Autores principales: Mishra, Rangnath, Simonson, Michael S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546189/
https://www.ncbi.nlm.nih.gov/pubmed/15642122
http://dx.doi.org/10.1186/1475-2840-4-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546189/
https://www.ncbi.nlm.nih.gov/pubmed/15642122
http://dx.doi.org/10.1186/1475-2840-4-2

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