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ER stress dependent microparticles derived from smooth muscle cells promote endothelial dysfunction during thoracic aortic aneurysm and dissection

The degeneration of vascular smooth muscle cell(s) (SMC) is one of the key features of thoracic aortic aneurysm and dissection (TAAD). We and others have shown that elevated endoplasmic reticulum (ER) stress causes SMC loss and TAAD formation, however, the mechanism of how SMC dysfunction contribute...

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Detalles Bibliográficos
Autores principales: Jia, Li-Xin, Zhang, Wen-Mei, Li, Tao-Tao, Liu, Yan, Piao, Chun-Mei, Ma, You-Cai, Lu, Yu, Wang, Yuan, Liu, Ting-Ting, Qi, Yong-Fen, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461939/
https://www.ncbi.nlm.nih.gov/pubmed/28468950
http://dx.doi.org/10.1042/CS20170252