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Gene expression profiling of tumours derived from ras(V12)/E1A-transformed mouse embryonic fibroblasts to identify genes required for tumour development
BACKGROUND: In cancer, cellular transformation is followed by tumour development. Knowledge on the mechanisms of transformation, involving activation of proto-oncogenes and inactivation of tumour-suppressor genes has considerably improved whereas tumour development remains poorly understood. An inte...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546195/ https://www.ncbi.nlm.nih.gov/pubmed/15651998 http://dx.doi.org/10.1186/1476-4598-4-4 |