Stable expression of constitutively-activated STAT3 in benign prostatic epithelial cells changes their phenotype to that resembling malignant cells

BACKGROUND: Signal transducers and activators of transcription (STATs) are involved in growth regulation of cells. They are usually activated by phosphorylation at specific tyrosine residues. In neoplastic cells, constitutive activation of STATs accompanies growth dysregulation and resistance to apo...

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Detalles Bibliográficos
Autores principales: Huang, Hosea F, Murphy, Thomas F, Shu, Ping, Barton, Arnold B, Barton, Beverly E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546221/
https://www.ncbi.nlm.nih.gov/pubmed/15647107
http://dx.doi.org/10.1186/1476-4598-4-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546221/
https://www.ncbi.nlm.nih.gov/pubmed/15647107
http://dx.doi.org/10.1186/1476-4598-4-2

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