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Effects of the cyclooxygenase-2 inhibitor nimesulide on cerebral infarction and neurological deficits induced by permanent middle cerebral artery occlusion in the rat

BACKGROUND: Previous studies suggest that the cyclooxygenase-2 (COX-2) inhibitor nimesulide has a remarkable protective effect against different types of brain injury including ischemia. Since there are no reports on the effects of nimesulide on permanent ischemic stroke and because most cases of hu...

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Detalles Bibliográficos
Autores principales: Candelario-Jalil, Eduardo, Mhadu, Noël H, González-Falcón, Armando, García-Cabrera, Michel, Muñoz, Eduardo, León, Olga Sonia, Fiebich, Bernd L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546225/
https://www.ncbi.nlm.nih.gov/pubmed/15656909
http://dx.doi.org/10.1186/1742-2094-2-3