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Single dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission in Cambodia: An open-label randomized trial

BACKGROUND: Single low dose primaquine (SLD PQ, 0.25mg/kg) is recommended in combination with artemisinin-based combination therapy (ACT) as a gametocytocide to prevent Plasmodium falciparum transmission in areas threatened by artemisinin resistance. To date, no randomized controlled trials have mea...

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Detalles Bibliográficos
Autores principales: Lin, Jessica T., Lon, Chanthap, Spring, Michele D., Sok, Somethy, Chann, Soklyda, Ittiverakul, Mali, Kuntawunginn, Worachet, My, Mok, Thay, Kheangheng, Rahman, Rifat, Balasubramanian, Sujata, Char, Mengchuor, Lanteri, Charlotte A., Gosi, Panita, Ubalee, Ratawan, Meshnick, Steven R., Saunders, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462369/
https://www.ncbi.nlm.nih.gov/pubmed/28591198
http://dx.doi.org/10.1371/journal.pone.0168702