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Single dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission in Cambodia: An open-label randomized trial
BACKGROUND: Single low dose primaquine (SLD PQ, 0.25mg/kg) is recommended in combination with artemisinin-based combination therapy (ACT) as a gametocytocide to prevent Plasmodium falciparum transmission in areas threatened by artemisinin resistance. To date, no randomized controlled trials have mea...
Autores principales: | Lin, Jessica T., Lon, Chanthap, Spring, Michele D., Sok, Somethy, Chann, Soklyda, Ittiverakul, Mali, Kuntawunginn, Worachet, My, Mok, Thay, Kheangheng, Rahman, Rifat, Balasubramanian, Sujata, Char, Mengchuor, Lanteri, Charlotte A., Gosi, Panita, Ubalee, Ratawan, Meshnick, Steven R., Saunders, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462369/ https://www.ncbi.nlm.nih.gov/pubmed/28591198 http://dx.doi.org/10.1371/journal.pone.0168702 |
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