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Efficacy of targeted drugs in germ cell cancer cell lines with differential cisplatin sensitivity

Testicular germ cell tumors (TGCTs) are the most common malignancies in men between the age of 15 and 35. Although cisplatin-based chemotherapy is highly effective in advanced disease, approximately 20% of patients have an unfavorable prognosis due to primary or acquired cisplatin resistance. For th...

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Detalles Bibliográficos
Autores principales: Schaffrath, Judith, Schmoll, Hans-Joachim, Voigt, Wieland, Müller, Lutz P., Müller-Tidow, Carsten, Mueller, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462387/
https://www.ncbi.nlm.nih.gov/pubmed/28591197
http://dx.doi.org/10.1371/journal.pone.0178930