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Efficacy of targeted drugs in germ cell cancer cell lines with differential cisplatin sensitivity
Testicular germ cell tumors (TGCTs) are the most common malignancies in men between the age of 15 and 35. Although cisplatin-based chemotherapy is highly effective in advanced disease, approximately 20% of patients have an unfavorable prognosis due to primary or acquired cisplatin resistance. For th...
Autores principales: | Schaffrath, Judith, Schmoll, Hans-Joachim, Voigt, Wieland, Müller, Lutz P., Müller-Tidow, Carsten, Mueller, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462387/ https://www.ncbi.nlm.nih.gov/pubmed/28591197 http://dx.doi.org/10.1371/journal.pone.0178930 |
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