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Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue

OBJECTIVE: Obesity is associated with an increased risk of diabetes mellitus, hypertension, and renal dysfunction. Angiotensin 1–7 and alamandine are heptameric renin angiotensin system peptide hormones. Further, alamandine levels increase with renal dysfunction. In the cardiovascular system, angiot...

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Detalles Bibliográficos
Autores principales: Uchiyama, Tsuyoshi, Okajima, Fumikazu, Mogi, Chihiro, Tobo, Ayaka, Tomono, Shoichi, Sato, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462406/
https://www.ncbi.nlm.nih.gov/pubmed/28591164
http://dx.doi.org/10.1371/journal.pone.0178769