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Effects of bevacizumab on endoplasmic reticulum stress in hypoxic retinal pigment epithelial cells

PURPOSE: To investigate the effects of bevacizumab on endoplasmic reticulum (ER) stress in human retinal pigment epithelial (RPE) cells cultured under hypoxic conditions. METHODS: RPE cells (ARPE–19) were cultured under hypoxic conditions (1% O(2)) with or without bevacizumab (0.3125 mg/mL) for 24 a...

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Detalles Bibliográficos
Autores principales: Park, Joo-Hee, Kim, Moosang, Oh, Jong-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462411/
https://www.ncbi.nlm.nih.gov/pubmed/28591217
http://dx.doi.org/10.1371/journal.pone.0179048