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Ribosome rearrangements at the onset of translational bypassing

Bypassing is a recoding event that leads to the translation of two distal open reading frames into a single polypeptide chain. We present the structure of a translating ribosome stalled at the bypassing take-off site of gene 60 of bacteriophage T4. The nascent peptide in the exit tunnel anchors the...

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Detalles Bibliográficos
Autores principales: Agirrezabala, Xabier, Samatova, Ekaterina, Klimova, Mariia, Zamora, Miguel, Gil-Carton, David, Rodnina, Marina V., Valle, Mikel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462505/
https://www.ncbi.nlm.nih.gov/pubmed/28630923
http://dx.doi.org/10.1126/sciadv.1700147