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Escaping mTOR inhibition for cancer therapy: Tumor suppressor functions of mTOR
A master promoter of cell growth, mammalian target of rapamycin (mTOR) is upregulated in a large percentage of cancer cells. Still, targeting mTOR using rapamycin has a limited outcome in patients. Our recent results highlight the additional role of mTOR as a tumor suppressor, explaining these modes...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462510/ https://www.ncbi.nlm.nih.gov/pubmed/28616576 http://dx.doi.org/10.1080/23723556.2017.1297284 |