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The autotaxin-lysophosphatidic acid pathway emerges as a therapeutic target to prevent liver cancer
Using transcriptome meta-analysis, we recently identified the autotaxin (ATX)-lysophosphatidic acid (LPA) pathway as a regulator of hepatocellular carcinoma (HCC) risk in human cirrhosis patients. Pharmacological targeting of this pathway reduced fibrosis progression and HCC development in animals,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462520/ https://www.ncbi.nlm.nih.gov/pubmed/28616586 http://dx.doi.org/10.1080/23723556.2017.1311827 |