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The MBD7 complex promotes expression of methylated transgenes without significantly altering their methylation status

DNA methylation is associated with gene silencing in eukaryotic organisms. Although pathways controlling the establishment, maintenance and removal of DNA methylation are known, relatively little is understood about how DNA methylation influences gene expression. Here we identified a METHYL-CpG-BIND...

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Detalles Bibliográficos
Autores principales: Li, Dongming, Palanca, Ana Marie S, Won, So Youn, Gao, Lei, Feng, Ying, Vashisht, Ajay A, Liu, Li, Zhao, Yuanyuan, Liu, Xigang, Wu, Xiuyun, Li, Shaofang, Le, Brandon, Kim, Yun Ju, Yang, Guodong, Li, Shengben, Liu, Jinyuan, Wohlschlegel, James A, Guo, Hongwei, Mo, Beixin, Chen, Xuemei, Law, Julie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462541/
https://www.ncbi.nlm.nih.gov/pubmed/28452714
http://dx.doi.org/10.7554/eLife.19893