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Sphingomyelin metabolism controls the shape and function of the Golgi cisternae

The flat Golgi cisterna is a highly conserved feature of eukaryotic cells, but how is this morphology achieved and is it related to its function in cargo sorting and export? A physical model of cisterna morphology led us to propose that sphingomyelin (SM) metabolism at the trans-Golgi membranes in m...

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Detalles Bibliográficos
Autores principales: Campelo, Felix, van Galen, Josse, Turacchio, Gabriele, Parashuraman, Seetharaman, Kozlov, Michael M, García-Parajo, María F, Malhotra, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462544/
https://www.ncbi.nlm.nih.gov/pubmed/28500756
http://dx.doi.org/10.7554/eLife.24603