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Treatment with anti-FcεRIα antibody exacerbates EAE and T-cell immunity against myelin

OBJECTIVE: To investigate the effects of targeting the high-affinity receptor for immunoglobulin E (FcεRI), that plays a central role in allergic responses and is constitutively expressed on mast cells and basophils, in clinical disease and autoimmune T-cell response in experimental MS. METHODS: Exp...

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Detalles Bibliográficos
Autores principales: Musio, Silvia, Costanza, Massimo, Poliani, Pietro Luigi, Fontana, Elena, Cominelli, Manuela, Abolafio, Gabriella, Steinman, Lawrence, Pedotti, Rosetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462602/
https://www.ncbi.nlm.nih.gov/pubmed/28616446
http://dx.doi.org/10.1212/NXI.0000000000000342