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Impairment of the activin A autocrine loop by lopinavir reduces self-renewal of distinct human adipose progenitors

Maintenance of the adipose tissue requires a proper balance between self-renewal and differentiation of adipose progenitors (AP). Any deregulation leads either to fat overexpansion and obesity or fat loss and consequent lipodystrophies. Depending on the fat pad location, APs and adipocytes are heter...

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Detalles Bibliográficos
Autores principales: Ravaud, Christophe, Paré, Martin, Azoulay, Stéphane, Dani, Christian, Ladoux, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462747/
https://www.ncbi.nlm.nih.gov/pubmed/28592814
http://dx.doi.org/10.1038/s41598-017-02807-9