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Impairment of the activin A autocrine loop by lopinavir reduces self-renewal of distinct human adipose progenitors
Maintenance of the adipose tissue requires a proper balance between self-renewal and differentiation of adipose progenitors (AP). Any deregulation leads either to fat overexpansion and obesity or fat loss and consequent lipodystrophies. Depending on the fat pad location, APs and adipocytes are heter...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462747/ https://www.ncbi.nlm.nih.gov/pubmed/28592814 http://dx.doi.org/10.1038/s41598-017-02807-9 |