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Overexpression of LINC00152 correlates with poor patient survival and knockdown impairs cell proliferation in lung cancer

We employed RNA sequencing analysis to reveal dysregulated lncRNAs in lung cancer utilizing 461 lung adenocarcinomas and 156 normal lung tissues from 3 separate cohorts. We found that LINC00152 was highly overexpressed in lung tumors as compared to their adjacent normal tissues. Patients with high L...

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Detalles Bibliográficos
Autores principales: Feng, Shumei, Zhang, Jie, Su, Wenmei, Bai, Shengbin, Xiao, Lei, Chen, Xiuyuan, Lin, Jules, Reddy, Rishindra M., Chang, Andrew C., Beer, David G., Chen, Guoan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462773/
https://www.ncbi.nlm.nih.gov/pubmed/28592840
http://dx.doi.org/10.1038/s41598-017-03043-x