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Platelet-rich plasma respectively reduces and promotes adipogenic and myofibroblastic differentiation of human adipose-derived stromal cells via the TGFβ signalling pathway

Autologous fat grafting is a gold standard therapy for soft tissue defects, but is hampered by unpredictable postoperative outcomes. Fat graft enrichment with adipose-derived stromal cell (ASCs) was recently reported to enhance graft survival. Platelet-rich plasma (PRP) has also emerged as a biologi...

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Detalles Bibliográficos
Autores principales: Chignon-Sicard, Bérengère, Kouidhi, Magali, Yao, Xi, Delerue-Audegond, Audrey, Villageois, Phi, Peraldi, Pascal, Ferrari, Patricia, Rival, Yves, Piwnica, David, Aubert, Jérôme, Dani, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462784/
https://www.ncbi.nlm.nih.gov/pubmed/28592806
http://dx.doi.org/10.1038/s41598-017-03113-0