Inhibition of AURKA kinase activity suppresses collective invasion in a microfluidic cell culture platform

Tumor local invasion is the first step of metastasis cascade which remains the key obstacle for cancer therapy. Collective cell migration plays a critical role in tumor invading into surrounding tissues. In vitro assays fail to assess collective invasion in a real time manner. Herein we aim to devel...

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Detalles Bibliográficos
Autores principales: Xia, Jiang-Long, Fan, Wen-Jun, Zheng, Fei-Meng, Zhang, Wen-Wen, Xie, Jia-Jun, Yang, Meng-Ying, Kamran, Muhammad, Wang, Peng, Teng, Hong-Ming, Wang, Chun-Li, Liu, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462816/
https://www.ncbi.nlm.nih.gov/pubmed/28592839
http://dx.doi.org/10.1038/s41598-017-02623-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462816/
https://www.ncbi.nlm.nih.gov/pubmed/28592839
http://dx.doi.org/10.1038/s41598-017-02623-1

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