Cargando…

Immunochemical Approach for Monitoring of Structural Transition of ApoA-I upon HDL Formation Using Novel Monoclonal Antibodies

Apolipoprotein A-I (apoA-I) undergoes a large conformational reorganization during remodeling of high-density lipoprotein (HDL) particles. To detect structural transition of apoA-I upon HDL formation, we developed novel monoclonal antibodies (mAbs). Splenocytes from BALB/c mice immunized with a reco...

Descripción completa

Detalles Bibliográficos
Autores principales: Kimura, Hitoshi, Mikawa, Shiho, Mizuguchi, Chiharu, Horie, Yuki, Morita, Izumi, Oyama, Hiroyuki, Ohgita, Takashi, Nishitsuji, Kazuchika, Takeuchi, Atsuko, Lund-Katz, Sissel, Akaji, Kenichi, Kobayashi, Norihiro, Saito, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462821/
https://www.ncbi.nlm.nih.gov/pubmed/28592796
http://dx.doi.org/10.1038/s41598-017-03208-8