CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

Large genome-mapping consortia and thousands of genome-wide association studies have identified non-protein coding elements in the genome as a having a central role in various biological processes. However, decoding the function of the millions of putative regulatory elements discovered in these stu...

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Detalles Bibliográficos
Autores principales: Klann, Tyler S., Black, Joshua B., Chellappan, Malathi, Safi, Alexias, Song, Lingyun, Hilton, Isaac B., Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462860/
https://www.ncbi.nlm.nih.gov/pubmed/28369033
http://dx.doi.org/10.1038/nbt.3853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462860/
https://www.ncbi.nlm.nih.gov/pubmed/28369033
http://dx.doi.org/10.1038/nbt.3853

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