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Investigations into the Sarcomeric Protein and Ca(2+)-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus)

Hypertrophic cardiomyopathy (HCM) is the most common single gene inherited cardiomyopathy. In cats (Felix catus) HCM is even more prevalent and affects 16% of the outbred population and up to 26% in pedigree breeds such as Maine Coon and Ragdoll. Homozygous MYBPC3 mutations have been identified in t...

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Detalles Bibliográficos
Autores principales: Messer, Andrew E., Chan, Jasmine, Daley, Alex, Copeland, O'Neal, Marston, Steven B., Connolly, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462916/
https://www.ncbi.nlm.nih.gov/pubmed/28642712
http://dx.doi.org/10.3389/fphys.2017.00348