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Epidermal growth factor prevents APOE4-induced cognitive and cerebrovascular deficits in female mice

Cerebrovascular dysfunction is re-emerging as a major component of aging, and may contribute to the risk of developing Alzheimer’s disease (AD). Two important risk factors for cerebrovascular dysfunction are APOE and female sex, which are primarily researched in the context of high amyloid-β (Aβ) le...

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Detalles Bibliográficos
Autores principales: Thomas, Riya, Morris, Alan W.J., Tai, Leon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463012/
https://www.ncbi.nlm.nih.gov/pubmed/28626809
http://dx.doi.org/10.1016/j.heliyon.2017.e00319