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Methylation Levels of LINE-1 As a Useful Marker for Venous Invasion in Both FFPE and Frozen Tumor Tissues of Gastric Cancer

Long interspersed nuclear element-1 (LINE-1) is a retrotransposon that contains a CpG island in its 5′-untranslated region. The CpG island of LINE-1 is often heavily methylated in normal somatic cells, which is associated with poor prognosis in various cancers. DNA methylation can differ between for...

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Detalles Bibliográficos
Autores principales: Min, Jimin, Choi, Boram, Han, Tae-Su, Lee, Hyuk-Joon, Kong, Seong-Ho, Suh, Yun-Suhk, Kim, Tae-Han, Choe, Hwi-Nyeong, Kim, Woo Ho, Hur, Keun, Yang, Han-Kwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463043/
https://www.ncbi.nlm.nih.gov/pubmed/28535662
http://dx.doi.org/10.14348/molcells.2017.0013