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MiR‐145 inhibits human colorectal cancer cell migration and invasion via PAK4‐dependent pathway

MicroRNA‐145 (miR‐145), as a tumor‐suppressive miRNA, has been demonstrated down‐regulated in colorectal cancer (CRC) cells, and could inhibit CRC cells growth. However, the molecular pathway in which miR‐145 modulates CRC malignant transformation has not been fully revealed. Here, we reported an in...

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Detalles Bibliográficos
Autores principales: Sheng, Nengquan, Tan, Gewen, You, Weiqiang, Chen, Hongqi, Gong, Jianfeng, Chen, Di, Zhang, Huizhen, Wang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463071/
https://www.ncbi.nlm.nih.gov/pubmed/28440035
http://dx.doi.org/10.1002/cam4.1029