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Epigenetic silencing of ADAMTS18 promotes cell migration and invasion of breast cancer through AKT and NF‐κB signaling

ADAMTS18 dysregulation plays an important role in many disease processes including cancer. We previously found ADAMTS18 as frequently methylated tumor suppressor gene (TSG) for multiple carcinomas, however, its biological functions and underlying molecular mechanisms in breast carcinogenesis remain...

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Detalles Bibliográficos
Autores principales: Xu, Hongying, Xiao, Qian, Fan, Yu, Xiang, Tingxiu, Li, Chen, Li, Chunhong, Li, Shuman, Hui, Tianli, Zhang, Lu, Li, Hongzhong, Li, Lili, Ren, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463072/
https://www.ncbi.nlm.nih.gov/pubmed/28503860
http://dx.doi.org/10.1002/cam4.1076