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Epigenetic silencing of ADAMTS18 promotes cell migration and invasion of breast cancer through AKT and NF‐κB signaling
ADAMTS18 dysregulation plays an important role in many disease processes including cancer. We previously found ADAMTS18 as frequently methylated tumor suppressor gene (TSG) for multiple carcinomas, however, its biological functions and underlying molecular mechanisms in breast carcinogenesis remain...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463072/ https://www.ncbi.nlm.nih.gov/pubmed/28503860 http://dx.doi.org/10.1002/cam4.1076 |