Cargando…

Screening for mismatch repair deficiency in colorectal cancer: data from three academic medical centers

Reflex immunohistochemistry (rIHC) for mismatch repair (MMR) protein expression can be used as a screening tool to detect Lynch Syndrome (LS). Increasingly the mismatch repair‐deficient (dMMR) phenotype has therapeutic implications. We investigated the pattern and consequence of testing for dMMR in...

Descripción completa

Detalles Bibliográficos
Autores principales: O'Kane, Grainne M., Ryan, Éanna, McVeigh, Terri P., Creavin, Ben, Hyland, John MP., O'Donoghue, Diarmuid P., Keegan, Denise, Geraghty, Robert, Flannery, Delia, Nolan, Carmel, Donovan, Emily, Mehigan, Brian J., McCormick, Paul, Muldoon, Cian, Farrell, Michael, Shields, Conor, Mulligan, Niall, Kennedy, Michael John, Green, Andrew J., Winter, Desmond C., MacMathuna, Padraic, Sheahan, Kieran, Gallagher, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463076/
https://www.ncbi.nlm.nih.gov/pubmed/28470797
http://dx.doi.org/10.1002/cam4.1025