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Adenosine Triphosphate Promotes Allergen-Induced Airway Inflammation and Th17 Cell Polarization in Neutrophilic Asthma

Adenosine triphosphate (ATP) is a key mediator to alert the immune dysfunction by acting on P2 receptors. Here, we found that allergen challenge caused an increase of ATP secretion in a murine model of neutrophilic asthma, which correlated well with neutrophil counts and interleukin-17 production. W...

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Detalles Bibliográficos
Autores principales: Zhang, Fang, Su, Xin, Huang, Gang, Xin, Xiao-Feng, Cao, E-Hong, Shi, Yi, Song, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463097/
https://www.ncbi.nlm.nih.gov/pubmed/28626774
http://dx.doi.org/10.1155/2017/5358647