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Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis

The purpose of this study was to investigate the role of oncostatin M (OSM) in tubulointerstitial lesion (TIL) in lupus nephritis (LN). We found that OSM was highly expressed in the renal tissue of LN mice. OSM is one of the interleukin-6 cytokine family members. In order to clarify the role and mec...

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Detalles Bibliográficos
Autores principales: Liu, Qingjuan, Du, Yunxia, Li, Kejun, Zhang, Wei, Feng, Xiaojuan, Hao, Jun, Li, Hongbo, Liu, Shuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463100/
https://www.ncbi.nlm.nih.gov/pubmed/28626343
http://dx.doi.org/10.1155/2017/3038514