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DNA methylation-based chromatin compartments and ChIP-seq profiles reveal transcriptional drivers of prostate carcinogenesis

BACKGROUND: Profiles of DNA methylation of many tissues relevant in human disease have been obtained from microarrays and are publicly available. These can be used to generate maps of chromatin compartmentalization, demarcating open and closed chromatin across the genome. Additionally, large sets of...

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Detalles Bibliográficos
Autores principales: Simmonds, Poppy, Loomis, Erick, Curry, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463361/
https://www.ncbi.nlm.nih.gov/pubmed/28592290
http://dx.doi.org/10.1186/s13073-017-0443-z