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Effects of amiodarone on short QT syndrome variant 3 in human ventricles: a simulation study
BACKGROUND: Short QT syndrome (SQTS) is a newly identified clinical disorder associated with atrial and/or ventricular arrhythmias and increased risk of sudden cardiac death (SCD). The SQTS variant 3 is linked to D172N mutation to the KCNJ2 gene that causes a gain-of-function to the inward rectifier...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463381/ https://www.ncbi.nlm.nih.gov/pubmed/28592292 http://dx.doi.org/10.1186/s12938-017-0369-0 |