Recent advances in the use of PI3K inhibitors for glioblastoma multiforme: current preclinical and clinical development

Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary tumor in the central nervous system. One of the most widely used chemotherapeutic drugs for GBM is temozolomide, which is a DNA-alkylating agent and its efficacy is dependent on MGMT methylation status. Little progress...

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Detalles Bibliográficos
Autores principales: Zhao, Hua-fu, Wang, Jing, Shao, Wei, Wu, Chang-peng, Chen, Zhong-ping, To, Shing-shun Tony, Li, Wei-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463420/
https://www.ncbi.nlm.nih.gov/pubmed/28592260
http://dx.doi.org/10.1186/s12943-017-0670-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463420/
https://www.ncbi.nlm.nih.gov/pubmed/28592260
http://dx.doi.org/10.1186/s12943-017-0670-3

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