Chemoresistance of colorectal cancer to 5-fluorouracil is associated with silencing of the BNIP3 gene through aberrant methylation

Purpose To investigate the correlation between chemoresistance of colorectal cancer to 5-fluorouracil and BNIP3 and the underlying mechanism. Methods BNIP3 protein in specimens was evaluated using immunohistochemistry. Semi-quantitative reverse transcription PCR and Western blot was employed to assa...

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Detalles Bibliográficos
Autores principales: He, Jianming, Pei, Li, Jiang, Heng, Yang, Weiwen, Chen, Jianfang, Liang, Houjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463433/
https://www.ncbi.nlm.nih.gov/pubmed/28607593
http://dx.doi.org/10.7150/jca.18171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463433/
https://www.ncbi.nlm.nih.gov/pubmed/28607593
http://dx.doi.org/10.7150/jca.18171

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