An "ex vivo model" contributing to the diagnosis and evaluation of new drugs in cystic fibrosis

Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane regulator (CFTR) gene. About 2000 mutations have been described so far. We setup an ex vivo model of human nasal epithelial cells (HNECs) to study CF patients testing the effect of novel m...

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Detalles Bibliográficos
Autores principales: Di Lullo, A.M., Scorza, M., Amato, F., Comegna, M., Raia, V., Maiuri, L., Ilardi, G., Cantone, E., Castaldo, G., Iengo, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore SRL 2017
Materias:
Rhinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463510/
https://www.ncbi.nlm.nih.gov/pubmed/27897275
http://dx.doi.org/10.14639/0392-100X-1328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463510/
https://www.ncbi.nlm.nih.gov/pubmed/27897275
http://dx.doi.org/10.14639/0392-100X-1328

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