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Virtual screening following rational drug design based approach for introducing new anti amyloid beta aggregation agent

Amyloid β (Aβ) sheets aggregations is the main reason of Alzheimer disease. The interacting areas between monomers are residue number 38 to 42. Inhibition of interaction between Aβ molecules prevents plaque formation. In the present study, we have performed a high-throughput virtual screening among...

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Detalles Bibliográficos
Autores principales: Rigi, Garshasb, Nakhaei, Mohammad Vala Ashdar, Eidipour, Hoda, Najimi, Arshia, Tajik, Fahimeh, Taher, Niloufar, Yarahmadi, Kamran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463618/
https://www.ncbi.nlm.nih.gov/pubmed/28642635
http://dx.doi.org/10.6026/97320630013042