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A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses

BACKGROUND. Glioblastoma (GBM) is the most common primary brain tumor, with dismal prognosis. The failure of drug–radiation combinations with promising preclinical data to translate into effective clinical treatments may relate to the use of simplified 2-dimensional in vitro GBM cultures. METHODS. W...

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Detalles Bibliográficos
Autores principales: Gomez-Roman, Natividad, Stevenson, Katrina, Gilmour, Lesley, Hamilton, Graham, Chalmers, Anthony J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463789/
https://www.ncbi.nlm.nih.gov/pubmed/27576873
http://dx.doi.org/10.1093/neuonc/now164