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Sugars Require Rigid Multivalent Displays for Activation of Mouse Sperm Acrosomal Exocytosis

[Image: see text] As a prerequisite to mammalian fertilization, the sperm acrosomal vesicle fuses with the plasma membrane and the acrosome contents are exocytosed. Induction occurs through engagement of the sperm receptors by multiple sugar residues. Multivalent polymers displaying mannose, fucose,...

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Detalles Bibliográficos
Autores principales: Huang, He, Rodolis, Maria T., Bhatia, Surita R., Sampson, Nicole S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464008/
https://www.ncbi.nlm.nih.gov/pubmed/28509550
http://dx.doi.org/10.1021/acs.biochem.7b00166