GEFs: Dual regulation of Rac1 signaling

GEFs play a critical role in regulating Rac1 signaling. They serve as signaling nodes converting upstream signals into downstream Rac1-driven cellular responses. Through associating with membrane-bound Rac1, GEFs facilitate the exchange of GDP for GTP, thereby activating Rac1. As a result, Rac1 unde...

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Detalles Bibliográficos
Autores principales: Marei, Hadir, Malliri, Angeliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464116/
https://www.ncbi.nlm.nih.gov/pubmed/27314616
http://dx.doi.org/10.1080/21541248.2016.1202635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464116/
https://www.ncbi.nlm.nih.gov/pubmed/27314616
http://dx.doi.org/10.1080/21541248.2016.1202635

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