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Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells

BACKGROUND: Pituitary tumor transforming gene1 (PTTG1) is a novel oncogene that is expressed in most tumors. It encodes a protein that is primarily involved in the regulation of sister chromatid separation during cell division. The oncogenic potential of PTTG1 has been well characterized in the mous...

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Detalles Bibliográficos
Autores principales: Hamid, Tariq, Malik, Mohammed T, Kakar, Sham S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546418/
https://www.ncbi.nlm.nih.gov/pubmed/15649325
http://dx.doi.org/10.1186/1476-4598-4-3