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Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells
BACKGROUND: Pituitary tumor transforming gene1 (PTTG1) is a novel oncogene that is expressed in most tumors. It encodes a protein that is primarily involved in the regulation of sister chromatid separation during cell division. The oncogenic potential of PTTG1 has been well characterized in the mous...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546418/ https://www.ncbi.nlm.nih.gov/pubmed/15649325 http://dx.doi.org/10.1186/1476-4598-4-3 |