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Genetic and epigenetic control of gene expression by CRISPR–Cas systems

The discovery and adaption of bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems has revolutionized the way researchers edit genomes. Engineering of catalytically inactivated Cas variants (nuclease-deficient or nuclease-deactivated [dCas]) co...

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Detalles Bibliográficos
Autores principales: Lo, Albert, Qi, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464239/
https://www.ncbi.nlm.nih.gov/pubmed/28649363
http://dx.doi.org/10.12688/f1000research.11113.1