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Pediatric high-grade glioma: biologically and clinically in need of new thinking

High-grade gliomas in children are different from those that arise in adults. Recent collaborative molecular analyses of these rare cancers have revealed previously unappreciated connections among chromatin regulation, developmental signaling, and tumorigenesis. As we begin to unravel the unique dev...

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Detalles Bibliográficos
Autores principales: Jones, Chris, Karajannis, Matthias A., Jones, David T. W., Kieran, Mark W., Monje, Michelle, Baker, Suzanne J., Becher, Oren J., Cho, Yoon-Jae, Gupta, Nalin, Hawkins, Cynthia, Hargrave, Darren, Haas-Kogan, Daphne A., Jabado, Nada, Li, Xiao-Nan, Mueller, Sabine, Nicolaides, Theo, Packer, Roger J., Persson, Anders I., Phillips, Joanna J., Simonds, Erin F., Stafford, James M., Tang, Yujie, Pfister, Stefan M., Weiss, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464243/
https://www.ncbi.nlm.nih.gov/pubmed/27282398
http://dx.doi.org/10.1093/neuonc/now101