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A better scoring model for de novo peptide sequencing: the symmetric difference between explained and measured masses

BACKGROUND: Given a peptide as a string of amino acids, the masses of all its prefixes and suffixes can be found by a trivial linear scan through the amino acid masses. The inverse problem is the ideal de novo peptide sequencing problem: Given all prefix and suffix masses, determine the string of am...

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Detalles Bibliográficos
Autores principales: Tschager, Thomas, Rösch, Simon, Gillet, Ludovic, Widmayer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464308/
https://www.ncbi.nlm.nih.gov/pubmed/28603547
http://dx.doi.org/10.1186/s13015-017-0104-1