Analgesic and anti‐inflammatory properties of novel, selective, and potent EP4 receptor antagonists

Prostaglandin (PG) E(2) is the key driver of inflammation associated with arthritic conditions. Inhibitors of PGE (2) production (NSAIDs and Coxibs) are used to treat these conditions, but carry significant side effect risks due to the inhibition of all prostanoids that play important physiological...

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Detalles Bibliográficos
Autores principales: Chandrasekhar, Srinivasan, Yu, Xiao‐Peng, Harvey, Anita K., Oskins, Jennifer L., Lin, Chaohua, Wang, Xushan, Blanco, Maria‐Jesus, Fisher, Matthew J., Kuklish, Steven L., Schiffler, Matthew A., Vetman, Tatiana, Warshawsky, Alan M., York, Jeremy S., Bendele, Alison M., Chambers, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464344/
https://www.ncbi.nlm.nih.gov/pubmed/28603634
http://dx.doi.org/10.1002/prp2.316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464344/
https://www.ncbi.nlm.nih.gov/pubmed/28603634
http://dx.doi.org/10.1002/prp2.316

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