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Acute and Protracted Cell Death in Light-Induced Retinal Degeneration in the Canine Model of Rhodopsin Autosomal Dominant Retinitis Pigmentosa

PURPOSE: To characterize a light damage paradigm and establish structural and immunocytochemical measures of acute and protracted light-induced retinal degeneration in the rhodopsin (RHO) T4R dog model of RHO–autosomal dominant retinitis pigmentosa (ADRP). METHODS: Retinal light damage was induced i...

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Detalles Bibliográficos
Autores principales: Sudharsan, Raghavi, Simone, Kristina M., Anderson, Nathan P., Aguirre, Gustavo D., Beltran, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464465/
https://www.ncbi.nlm.nih.gov/pubmed/28114588
http://dx.doi.org/10.1167/iovs.16-20749