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Effects of microRNA-223 on morphine analgesic tolerance by targeting NLRP3 in a rat model of neuropathic pain

OBJECTIVE: To investigate the effects of microRNA-223 on morphine analgesic tolerance by targeting NLRP3 in a rat model of neuropathic pain. METHODS: Our study selected 100 clean grade healthy Sprague-Dawley adult male rats weighing 200 to 250 g. After establishment of a rat model of chronic constri...

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Detalles Bibliográficos
Autores principales: Xie, Xiao-Juan, Ma, Li-Gang, Xi, Kai, Fan, Dong-Mei, Li, Jian-Guo, Zhang, Quan, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464520/
https://www.ncbi.nlm.nih.gov/pubmed/28580822
http://dx.doi.org/10.1177/1744806917706582