Genetic variants in ALDH1B1 and alcohol dependence risk in a British and Irish population: A bioinformatic and genetic study

Alcohol is metabolized in the liver via the enzymes alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Polymorphisms in the genes encoding these enzymes, which are common in East Asian populations, can alter enzyme kinetics and hence the risk of alcohol dependence and its sequelae. One o...

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Detalles Bibliográficos
Autores principales: Way, Michael J., Ali, M. Adam, McQuillin, Andrew, Morgan, Marsha Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464525/
https://www.ncbi.nlm.nih.gov/pubmed/28594837
http://dx.doi.org/10.1371/journal.pone.0177009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464525/
https://www.ncbi.nlm.nih.gov/pubmed/28594837
http://dx.doi.org/10.1371/journal.pone.0177009

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